Video Statements
Video statements from consortium members, recorded at the first partner meeting in April 2026
First Partner Meeting
April 21st/22nd – A historic moment for healthy longevity science In Switzerland, the Swiss Campus for Healthy Longevity at the University of Basel hosted the first partner meeting of the Global Health Span Extension Consortium, a truly historic event for the future of… Read More »First Partner Meeting
DunedinPACE activity
A third generation DNAm clock that measures the speed of aging Global Health Span Extension Consortium activity by Terrie E. Moffitt, MBE, PhD Terry Moffitt is a partner of the Global Health Span Consortium and leads the team that developed… Read More »DunedinPACE activity
Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial
While observational studies and small pilot trials suggest that vitamin D, omega-3 and exercise may slow biological aging, larger clinical trials testing these treatments individually or in combination are lacking. Here, we report the results of a post hoc analysis… Read More »Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial
ICOPE Trial
The WHO defined 6 key functions that people value most, including mobility, cognition, nutrition/vitality, mental health, vision and hearing, which as a composite outcome define intrinsic capacity. To monitor and strengthen intrinsic capacity, the WHO established the ICOPE, which has been increasingly adopted by researchers and clinicians… Read More »ICOPE Trial
repurposing 10 RCTs with IC as outcome
We harmonize 10 clinical trials with phenotyping on ICOPE functions “mobility, mental health, cognition, vision, hearing and nutrition/vitality”. The consortium defined a shared concept on how to derive the composite endpoint “intrinsic capacity” from the six ICOPE functions to repurpose… Read More »repurposing 10 RCTs with IC as outcome
XPRIZE Healthspan competition
For the RCT, we first propose a two-arm randomized controlled pilot trial that will enroll 10 participants for the XPRIZE Semi-Finals to evaluate the effects of our personalized multimodal lifestyle intervention combined with our all-in-one supplement. After a screening process… Read More »XPRIZE Healthspan competition