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Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial

While observational studies and small pilot trials suggest that vitamin D, omega-3 and exercise may slow biological aging, larger clinical trials testing these treatments individually or in combination are lacking. Here, we report the results of a post hoc analysis… Read More »Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial

ICOPE Trial

The WHO defined 6 key functions that people value most, including mobility, cognition, nutrition/vitality, mental health, vision and hearing, which as a composite outcome define intrinsic capacity. To monitor and strengthen intrinsic capacity, the WHO established the ICOPE, which has been increasingly adopted by researchers and clinicians… Read More »ICOPE Trial